Instgra 50 mg (Dolutegravir) – Effective Antiretroviral HIV‑1 Treatment
Instgra 50 mg (Dolutegravir): Integrase Strand Transfer Inhibitor for HIV‑1
Instgra 50 mg (Dolutegravir) is an antiretroviral medication containing Dolutegravir, used to treat HIV‑1 infection in adults and children above approximately 30 kg. It belongs to the integrase strand transfer inhibitor (INSTI) class, which works by blocking the HIV integrase enzyme—preventing the virus from integrating into human DNA and replicating.
This medicine is always prescribed in combination with other antiretroviral agents to effectively reduce viral load, enhance immune function (including CD4 count), and help prevent progression to AIDS.
🔍 Key Benefits:
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Contains potent Dolutegravir 50 mg
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Blocks HIV‑1 replication at the integrase step
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Lowers viral load and supports immune recovery
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Once-daily oral tablet
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Can be taken with or without food
🩺 How to Use:
Take one tablet once daily or as directed by a healthcare provider. Swallow the tablet whole with water—do not crush or chew. Consistency and timing support maximum benefit.
⚠️ Possible Side Effects:
Common side effects include:
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Headache
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Insomnia or sleep disturbances
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Fatigue or general discomfort
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Nausea, diarrhea, abdominal pain
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Rash
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Increased liver enzymes and rare liver dysfunction.
These are usually mild and resolve over time. Consult your doctor if any persist or worsen.
🚫 Warnings & Precautions:
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Do not use if allergic to Dolutegravir or any ingredient
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Avoid co-administration with dofetilide due to serious interactions
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Monitor liver function in patients with hepatitis B or C, or existing liver disease
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Use caution if operating machinery or driving, due to possible dizziness or fatigue
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Alcohol may increase risk of liver-related side effects—consult your doctor
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Special caution advised during pregnancy—especially during first trimester—and while breastfeeding,
💊 Directions for Missed or Overdose:
If you miss a dose, take it as soon as you remember unless the next dose is within ≥4 hours. Do not double-dose. In case of overdose, seek immediate medical advice with the medicine pack.
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